Dr Apul Parikh Leads Breakthrough Study Using Diluted HArmonyCa™ for Neck Rejuvenation

At the Apul Parikh Clinic, we are proud to share an exciting development in non-surgical aesthetic treatment. Dr Apul Parikh, a leading expert in aesthetic injectables and internationally respected trainer, has authored a pioneering study on the use of diluted HArmonyCa™ for neck rejuvenation, marking the first published case series of its kind.

This study not only reflects Dr Parikh’s dedication to clinical research and safe innovation, but also opens up a new, evidence-based treatment pathway for patients seeking natural, visible improvement in the neck area; an area historically difficult to treat with injectables alone.

Download the study here.

Why Neck Rejuvenation Matters

While facial rejuvenation treatments are widely popular, the neck is increasingly becoming an area of concern for patients. The skin on the neck is thinner, more delicate, and often shows signs of ageing, such as creases, laxity, and horizontal lines, earlier than the face. For many, it can betray age even when the face appears smooth and refreshed.

However, non-surgical options for treating the neck have traditionally been limited, especially when it comes to injectable treatments. Many dermal fillers are not considered suitable due to the delicate anatomy and risk of visible product or irregularities. That’s what makes Dr Parikh’s work so significant; it suggests a way forward using an innovative, carefully diluted biostimulatory filler.

About the Study: A First of Its Kind

The case series involved two female patients seeking treatment for transverse neck lines, those horizontal creases that can deepen with age and repetitive motion. Dr Parikh used a pioneering technique with HArmonyCa™ with saline, allowing for a softer, more diffuse application suited to the neck’s delicate tissue.

The results were assessed using two widely accepted, validated scales:

  • The Global Aesthetic Improvement Scale (GAIS), which measures overall improvement as seen by both the patient and practitioner.
  • The Allergan Transverse Neck Line (ATNL) Scale, a clinical tool that grades the severity of neck lines on a scale from mild to severe.

The outcomes were impressive:

  • Both patients showed clear, measurable improvement in their neck lines.
  • One patient improved from a “moderate” rating to “mild,” while the other shifted from “severe” to “mild.”
  • No side effects or adverse reactions were recorded, and the treatment was well tolerated.

This significant case series offers the first clinical insight into the use of dilute HArmonyCa™ in the neck and sets the stage for larger-scale research with longer-term follow-up.

Why This Research Is Important

This isn’t just an incremental advance, it’s a meaningful step forward for aesthetic medicine. Until now, practitioners have had to rely on anecdotal evidence or off-label use without clinical data to support the effectiveness of injectables in the neck. Dr Parikh’s work begins to change that.

By carefully documenting his method, patient outcomes, and safety data, Dr Parikh is helping to build a more evidence-based foundation for aesthetic treatment in an area of growing patient demand. For patients, this means greater confidence, improved treatment outcomes, and the reassurance that procedures are backed by both experience and data.

It also reinforces the idea that true innovation in aesthetics isn’t just about trends, it’s about progress built on science, safety, and transparency.

What Makes HArmonyCa™ Different?

HArmonyCa™ is an advanced injectable that combines two clinically proven ingredients: hyaluronic acid (HA), which hydrates and smooths the skin, and calcium hydroxyapatite (CaHA), which stimulates the production of collagen. The product offers both immediate lifting and long-term structural improvement, making it a unique hybrid filler.

While its application in the mid-face and jawline has been widely adopted, the use of HArmonyCa™ in the neck has remained largely unexplored until now. Dr Parikh’s case series explores what happens when the product is diluted and used with precision in this sensitive area, offering new potential for non-surgical neck rejuvenation.

Could Diluted HArmonyCa™ Be Right for You?

HArmonyCa™ is an advanced injectable that combines two clinically proven ingredients: hyaluronic acid (HA), which hydrates and smooths the skin, and calcium hydroxyapatite (CaHA), which stimulates the production of collagen. The product offers both immediate lifting and long-term structural improvement, making it a unique hybrid filler.

While its application in the mid-face and jawline has been widely adopted, the use of HArmonyCa™ in the neck has remained largely unexplored until now. Dr Parikh’s case series explores what happens when the product is diluted and used with precision in this sensitive area, offering new potential for non-surgical neck rejuvenation.

Aesthetic Treatment Authority You Can Trust in London

Dr Apul Parikh has long been recognised as one of the UK’s leading voices in cosmetic injectables. As a globally respected speaker, trainer, and hands-on practitioner, he regularly educates other doctors and nurses on advanced techniques in Botox, Dermal Fillers, and facial anatomy.

This study is the latest example of how he continues to lead from the front—by contributing to the scientific literature, shaping industry standards, and always putting patient safety first. His deep understanding of product science, facial dynamics, and injection technique is what sets his practice apart.

For existing patients, this announcement reaffirms what they already know: they are in the safest, most capable hands. For prospective clients, it offers compelling reassurance that at Apul Parikh Clinic, your treatment is grounded in both experience and evidence.

Could Diluted HArmonyCa™ Be Right for You?

To learn more about neck treatments or to explore whether diluted HArmonyCa™ might be appropriate for your goals, we welcome you to book a consultation with Dr Parikh. Whether you’re new to aesthetic medicine or exploring advanced treatments, you’ll receive clear advice, expert care, and a bespoke approach tailored to you.